منابع مشابه
Genetic Co-Occurrence Network across Sequenced Microbes
The phenotype of any organism on earth is, in large part, the consequence of interplay between numerous gene products encoded in the genome, and such interplay between gene products affects the evolutionary fate of the genome itself through the resulting phenotype. In this regard, contemporary genomes can be used as molecular records that reveal associations of various genes working in their na...
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Improving knowledge worker productivity has been one of the most important tasks of the century. However, we have few measures or management interventions to make such improvement possible, and it is difficult to identify patterns that should be followed by knowledge workers because systems and processes in an organization are often regarded as a death blow to creativity. In this paper, we se...
متن کاملSupporting Information of “Genetic Co-Occurrence Network Across Sequenced Microbes”
Quantification of correlogy and anti-correlogy We downloaded orthology data from the Kyoto Encyclopedia of Genes and Genomes (KEGG, November 2009) [1], and surveyed the presence or absence of each ortholog across different bacterial species. To avoid possible biases arising from redundant genomes, we considered only one subspecies from each species if it contains multiple subspecies. Also, we e...
متن کاملRapid SNP Discovery and Genetic Mapping Using Sequenced RAD Markers
Single nucleotide polymorphism (SNP) discovery and genotyping are essential to genetic mapping. There remains a need for a simple, inexpensive platform that allows high-density SNP discovery and genotyping in large populations. Here we describe the sequencing of restriction-site associated DNA (RAD) tags, which identified more than 13,000 SNPs, and mapped three traits in two model organisms, us...
متن کاملDeveloping Genetic Maps
We can determine θs for pairs of genes or loci. Next question is how to place them in a genetic map; i.e., grouping loci into linkage groups and ordering sets of 3 or more loci. 1. Grouping loci into linkage groups The question beyond determining linkage of any two loci is the ordering of the loci into a reasonable genetic map. Ordering can be done using the MLE of θ, determined via a two-point...
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ژورنال
عنوان ژورنال: Nature Reviews Genetics
سال: 2013
ISSN: 1471-0056,1471-0064
DOI: 10.1038/nrg3528